Ttp Pregnancy Symptoms

In acquired ttp the body.

Ttp pregnancy symptoms. Thrombotic thrombocytopenic purpura ttp is a rare disorder that affects your blood s tendency to clot. Or symptoms of ttp. The time of occurrence during pregnancy was reported in 18 case series 53 pregnancies. Thrombotic thrombocytopenic purpura ttp occurs more commonly in women and so can be associated with pregnancy.

In this disease tiny clots form throughout your body. Thrombotic thrombocytopenic purpura ttp is a problem of blood vessels that sometimes develops during pregnancy either as a complication of a disease or independently. Thrombotic thrombocytopenic purpura ttp information for patients. The occurrence of pregnancy or postpartum among women with thrombotic thrombocytopenic purpura hemolytic uremic syndrome ttp hus was reported in 25 case series.

Symptoms may include large bruises fever weakness shortness of breath confusion and headache. Thrombotic thrombocytopenic purpura ttp is an acute rare potentially life threatening disorder presenting with thrombocytopenia hemolytic anemia and clinical consequences of microvascular thrombosis caused by deficiency of adamts13. In ttp blood clots form in small blood vessels throughout the body. Ttp occurring in early trimester is uncommon and is also associated with great maternal and fetal mortality.

The time during pregnancy with greatest risk for development of ttp is near term and during the post partum period. 1 2 the majority of acute cases are acquired autoantibody mediated and characterized by low adamts13 activity 10 and the presence of anti adamts13. It is not usually known what triggers acquired ttp but it can be triggered by pregnancy or a recent virus. This results in a low platelet count low red blood cells due to their breakdown and often kidneys heart and brain dysfunction.

The clots can limit or block the flow of oxygen rich blood to the body s organs such as the brain kidneys and heart.